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Tranq (Xylazine): The Veterinary Tranquilizer Invading the Street Drug Scene

Tranq, or xylazine, is a drug that many people might not be familiar with. This veterinary tranquilizer, commonly used on animals, is now finding its way into the illegal drug market, often being mixed with other substances such as cocaine, heroin, and fentanyl.

This article aims to inform and educate recreational drug users, parents, and the general public about the dangers of tranq, as well as discussing harm reduction solutions using analytical reagent testing kits such as those provided by WIM Scientific Laboratories.

What is Xylazine?

Xylazine is a non-opioid sedative and muscle relaxant that is primarily used in veterinary medicine to sedate large animals like horses, cows, and deer. The drug works by depressing the central nervous system, causing sedation, analgesia (reduced pain), and muscle relaxation. In animals, it is commonly used as a pre-anesthetic or for minor surgical procedures.

However, xylazine has made its way into the human drug market, where it is often mixed with other substances to increase the sedative effect or to cut the amount of actual drugs being sold. The drug has become increasingly popular, particularly when combined with opioids like heroin or fentanyl. In Canada, xylazine first appeared in significant quantities in the drug market in 2019. Since 2012, most xylazine detections have occurred in Ontario, followed by British Columbia and Alberta.

Health officials in both the US and Canada are becoming increasingly concerned about the drug, which can have dangerous and potentially fatal effects when used recreationally or when mixed with other substances.

Effects of Xylazine on Humans

When used on humans, xylazine can cause various sedative effects that can slow down brain activity, lower blood pressure, heart rate, and breathing rate. Some users may experience a feeling of relaxation, drowsiness, or euphoria. However, these effects can be hazardous, especially when combined with other substances that depress the central nervous system, such as opioids, alcohol, or other sedatives.

The combination of xylazine with opioids like fentanyl can be particularly dangerous, as it increases the risk of overdose and death. Symptoms of a xylazine overdose may include severe drowsiness, difficulty breathing, slow or irregular heartbeat, and unconsciousness. In severe cases, an overdose can lead to coma or death.

The Dangers of Mixing Xylazine with Other Drugs

The increasing prevalence of xylazine in the street drug market is particularly concerning because it is often mixed with other substances without the knowledge of the user. This can lead to dangerous interactions and increased risk of overdose.

For example, mixing xylazine with stimulants like cocaine can create a potentially dangerous combination. The sedative effects of xylazine may, at first, counteract the stimulating effects of cocaine, causing the user to take more of the substance in search of a high. Once the stimulating effects of the cocaine wear off, the user may experience a sudden and severe increase in the sedative effects of xylazine, leading to an increased risk of overdose.

Similarly, mixing xylazine with alcohol or other depressants can lead to a dangerous interaction that can significantly increase the risk of an overdose. The combined depressant effects of these substances can lead to respiratory depression, slowing or stopping breathing, unconsciousness, and even death.

Harm Reduction Strategies

Given the risks associated with xylazine and its increasing prevalence in the street drug market, it is essential for drug users and their loved ones to be aware of harm reduction strategies. One such strategy is the use of analytical reagent testing kits, such as those provided by WIM Scientific Laboratories.

Analytical Reagent Testing Kits

WIM Scientific Laboratories offers Marquis Reagents, which are simple and effective testing kits that can help users identify the presence of xylazine and other substances in their drugs. These kits use a chemical reagent that, when mixed with a small sample of the substance being tested, will produce a color change that can help to identify the presence of specific drugs or adulterants.

Using a Marquis Reagent testing kit can help users to make informed decisions about the substances they are consuming and potentially avoid dangerous combinations or adulterated drugs. These kits can be a valuable harm reduction tool for recreational drug users who want to minimize the risks associated with drug use.

To use a Marquis Reagent testing kit, follow these simple steps:

  1. Obtain a small sample of the substance you wish to test.
  2. Place the sample on a clean, non-porous surface, such as glass or ceramic.
  3. Add one or two drops of the Marquis Reagent to the sample.
  4. Observe the color change that occurs.
  5. Compare the color change to the provided reference chart to help identify the presence of specific substances or adulterants.

Additional Harm Reduction Strategies

In addition to using reagent testing kits, there are other harm reduction strategies that can help minimize the risks associated with drug use:

  • Know the source of your drugs. If possible, try to obtain drugs from a trusted and reliable source.
  • Start with a small dose. If you are unsure of the potency or composition of a substance, it is always advisable to start with a small dose and wait to see the effects before taking more.
  • Avoid mixing substances. Combining drugs, especially those that depress the central nervous system, can lead to dangerous interactions and increased risk of overdose.
  • Use with others. If possible, try to use drugs in the presence of others who can monitor for signs of an overdose and call for help if needed.
  • Carry naloxone. Naloxone is a medication that can reverse the effects of an opioid overdose. While it may not be effective in reversing a xylazine overdose, it can still be a life-saving tool if opioids are also present.


The rise of xylazine, or tranq, in the street drug market is a concerning development that poses significant risks to drug users. By understanding the dangers associated with this drug and employing harm reduction strategies such as using Marquis Reagent testing kits from WIM Scientific Laboratories, users and their loved ones can help to minimize these risks and make more informed decisions about drug use.

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Molly Testing and Harm Reduction

Molly, also known as ecstasy, is a drug that can be mixed with other harmful drugs. However, some organizations test pills for purity at music festivals and raves to keep people safe.

These organizations, known as harm reduction services, use chemical testing kits to help attendees determine the purity of their drugs. These services have decreased the consumption of dangerous drugs and the risk of overdoses and other negative consequences.

Real-Time Testing

Molly is an illegal drug that has become increasingly dangerous over the years. In recent years, it has been mixed with various chemicals that make it toxic and, in some cases, deadly.

In the US, scientists and public health experts have started to show up at music festivals, concerts, raves, and other events where illicit drugs are a common occurrence to help people test pills for purity in real-time so that they can make informed decisions about whether they should use them or not. Equipped with special chemical testing kits, they work with attendees to determine what pills and powders are made of and how strong they are.

These volunteers are a part of the harm reduction movement, which is dedicated to preventing and reducing the use of illegal substances and other high-risk behaviors. Proponents of these programs argue that they can save lives by encouraging people not to take illegal drugs and preventing overdoses.

A study conducted by Johns Hopkins University researchers found that pill-testing services, free and offered on-site at dance parties and other events in the United States, can be a valuable tool to fight the spread of this harmful drug. The results suggest that several people may choose not to take illegal drugs if they learn they are fake or adulterated.

This is because users who can test their drugs for purity and potency are more likely to reject them, which can reduce the risk of overdoses or other harm. In addition, they are more likely to follow safety instructions and make safer choices while at the party.

One of the main problems with ecstasy, also known as Molly, is it’s highly addictive. It can cause people to become depressed, have difficulty sleeping, and lose control of their bodies. It’s also been linked to severe health effects, including brain damage, seizures, and death.

This is why some countries like Portugal have opted for a harm reduction approach that encourages the testing of drugs and has proven to be successful in lowering the rate of drug abuse, overdoses, and related fatalities. While it’s a step in the right direction, more must be done to reduce the risks of this dangerous drug. For example, police and public health could agree on amnesty stations where users can bring their drugs for a quick drug test. This would lower the number of deaths and hospitalizations while also helping to keep local drug trends in check.

Preventing Overdoses

Fentanyl test strips, or FTS, are a simple, cheap, and evidence-based method of preventing overdose. They can be a lifesaver for the teen experimenting for the first time or an individual in the throes of a severe opioid use disorder. This concert-goer wants to have a safe trip or someone years into recovery.

The ubiquity of fentanyl and its analogs – 50 to 100 times stronger than morphine – has contributed to the rise in overdose deaths nationwide. These drugs are often mixed in cocaine, heroin, MDMA/ecstasy/Molly, or pressed into pills sold on the street. Many users are unaware that these contaminated drugs are dangerous, even deadly.

Because fentanyl and its analogs are so easily mixed into street drugs, knowing what you’re taking is challenging. As a result, many people have unwittingly taken more than they should and suffering from an overdose.

It’s hazardous when using MDMA (also known as Molly or Ecstasy) or molly-laced drugs such as bath salts, which can cause severe overstimulation and delirium. These narcotics can be mixed with MDMA to increase their potency.

Another drug that can lead to overdoses is MDPV, a synthetic cannibal compound commonly pressed into drugs. This substance is ten times more potent than MDMA and can cause fatal overstimulation or delirium.

These substances can be identified by using Marquis, Mecke, and Simon’s tests. The first two are used to identify the main chemical of the drug, and the third is used to differentiate MDMA from MDA, a related compound that is similar to MDMA but has other dangerous additives.

In the case of MDMA, a negative result from the first two tests is indicative that you aren’t taking the real thing. However, you may need to take a more advanced test like the Froehde or the 5-APB/ 6-APB testing kits if you are dealing with other chemicals that could be hazardous.

In a study by researchers from Brown University and Brown University School of Public Health, young adults who used FTS and reported positive test results were four times more likely to report increased overdose safety than those who did not use FTS. This could represent an essential addition to current overdose prevention efforts, particularly when combined with other evidence-based strategies, such as engaging people who use drugs to access addiction treatment and other services.

Preventing Infections

Ecstasy (or “molly”) is a powerful, synthetic stimulant drug found to cause serious health consequences in young people. It has hallucinogenic and stimulating effects lasting 3-6 hours. It is often snorted, smoked, or injected.

In addition to MDMA, many Molly drugs are laced with other potentially dangerous drugs. These include cocaine, ketamine, methamphetamine, over-the-counter cough medicine, or synthetic cathinone, known as “bath salts.”

It is vital to know what your medication is made of to avoid being infected by these chemicals. When you purchase a pill, capsule, or powder sold as Molly, make sure it is only made from MDMA and not laced with other substances.

If you are still determining what you have, several tests can help you determine what you have. These tests include the Marquis test, Simon’s test, and the Froehde test kit.

The Marquis test detects the chemical MDMA, one of the most common tests for this drug. This test is also sensitive enough to identify other drugs, including 5-APB and 6-APB, often sold as fake ecstasy.

Similarly, the Froehde test can identify other drugs found in Molly, including the dangerous cuts PMA and PMMA. These cuts are more likely to kill someone with just one dose than most other drugs, so you must have these test kits to know what you have in your possession.

These test kits are great to have on hand, primarily if you work in an environment with a high risk of exposure to Molly. They can save lives by preventing the misuse and abuse of this drug.

In addition to reducing risks of injury or death, these test kits can prevent infections caused by this drug. Moreover, they can save money for the organization implementing these tests. This makes them an ideal investment. As a result, these test kits are becoming an essential part of harm reduction efforts worldwide. They can also be an excellent addition to any school or workplace safety program.

Educating People

Whether you’re planning on taking MDMA at Spring Fling or another event, it’s essential to know that if you’re going to take a drug like Molly, you should only take it under the supervision of a medical professional. Getting the correct information before you consume a drug can help save your life.

Many psychedelic communities embrace harm reduction tactics, such as drug testing, because they’re a way to minimize the risks of consuming fake or adulterated drugs. These services help people trying ecstasy for the first time avoid potentially deadly doses of chemicals such as fentanyl.

One of the most common drugs sold as ecstasy or Molly is a synthetic psychoactive substance called methylenedioxymethamphetamine, or MDMA. It is known for creating euphoria and heightened sensations; this drug is often pressed into pills or sold in powder form. It’s been linked to increased deaths, so festival-goers must be tested for purity.

Several organizations have recently started distributing drug-testing kits at music festivals to test whether attendees’ ecstasy and Molly capsules are pure or laced with other drugs. Those who receive the results can decide if they want to continue using and take it safely or if they should seek medical attention for further testing.

But while drug-testing organizations need to be transparent about their practices, festival-goers must also understand how these programs work and why they’re needed. Besides providing real-time, on-site drug testing to reduce the risk of overdoses and infections, drug-testing sites can provide valuable epidemiological data to help improve national Drug Action Plans and prevent deaths.



Contributing to Psychedelic Research

As psychedelics make their way back into the laboratory for a 21st-century revival, scientists and researchers explore their incredible potential to change the brain.

Clinicians who work with clients using psychedelics are uniquely positioned to contribute to this research and help shape public policy. This article outlines how to do that safely and ethically.

Research Methods

Contributing to psychedelic research requires several different approaches. It may include using a harm-reduction approach to psychedelic use, incorporating psychedelics into psychotherapy, or pursuing further research on specific psychedelic compounds.

Harm reduction is a therapeutic approach to drug use that emphasizes the need to maximize the positive effects of drugs while minimizing their negative ones. It also seeks to avoid overly abstinence-oriented practices and pathologizing the use of certain drugs. This approach is commonly applied to marijuana and MDMA but may also apply to other psychedelics, such as LSD and psilocybin.

In applying this approach, therapists often clarify the client’s motivation for psychedelic use. This may help to prevent clients from obtaining a substance for which they are not fully prepared and could lead to harmful consequences such as dependency or overdose. Clinicians can then assist clients in identifying alternative pathways that are available to achieve their desired goals while avoiding the need for illegal psychedelics.

Another way therapists can contribute to psychedelic research is by examining the role that psychedelics play in other cultures and contexts. For example, psychedelics are used in many sacramental settings that have been practiced for centuries to facilitate spiritual experiences.

Similarly, psychedelics are commonly used in less controlled settings, such as concerts or festivals. Despite these settings’ increased likelihood of adverse events, numerous benefits can be gained from engaging in these activities. These benefits include enhanced social interactions, increased self-awareness, and community.

As a result, therapists may wish to encourage clients to consider seeking treatment for mental health issues before they pursue psychedelic use in these settings. This is particularly true for classic psychedelics, which are safe and have a low potential for physical or psychological harm when used under appropriate conditions.

In addition, therapists can help to inform clients about the risks of obtaining psychedelics from underground guides who are not subject to regulatory oversight. These guides often have little experience with psychedelics and lack the skills to protect their clients from dangerous conditions. Additionally, a client who is unaware of these risks can be at risk of experiencing a “bad trip.” In these cases, a therapist might use harm reduction principles to guide the client to a safer experience and may help them to assess the safety and trustworthiness of an underground guide.


Replication of research results is a fundamental part of high-quality psychedelic research. Repeated replication is needed to determine confidence in a finding and resolve arguments about the evidence for that claim. It is also helpful to improve the theoretical specificity of a claim by repeatedly testing replicability and generalizability across units, treatments, outcomes, and settings that might be relevant to the claim.

With repeated failures, the generalizability and replicability space shrink until the theory is so weak that it does not commit replicability.

Several factors influence the choice of whether or when to attempt a replication. Journals would prefer to wait for a result before accepting an experimental manuscript, and authors, on the other hand, may wish to see the results replicated before publication to minimize impacts on their work.

For a study to be considered a replication, it must follow the same procedures and under similar conditions as the original. Yet even in the best-case scenario, the replication team can only partially duplicate a previous event. Instead, they must use a prediction interval based on the original d, a sample size used to estimate it, and the proposed replication sample size.

This approach has been used in many replication studies, and it is a promising way to address the challenges of establishing and documenting the power of a new effect. But it is still a complex process that requires much time and resources.

The challenge of defining what qualifies as a replicative effect affects research in multiple fields, including psychedelic science.


Ethics is a branch of philosophy that examines what is right or wrong, morally good or bad. It is often confused with morality, but that term generally refers to a specific set of beliefs and practices about what it is morally proper or incorrect to do in a given situation.

Psychedelic drugs such as LSD, magic mushrooms, and MDMA have gained much attention in scientific and medical circles because of their potential for treating anxiety disorders and emotional trauma. They may be able to rewire the brain and offer relief from negative emotions that can cause depression or substance abuse problems, according to Johns Hopkins University researcher Dr. Frederick Barrett.

However, before these suitable substances are available for medical treatment, researchers must establish their safety and efficacy. To that end, several ethical principles need to be applied to these studies.

One of these principles is the principle of replication. It is a cornerstone of the scientific method and should be adhered to when conducting psychedelic research.

Another essential principle is that researchers should be committed to conducting their studies to protect participants’ health and well-being. This is particularly true of clinical trials.

The principle of confidentiality is also a significant issue that must be considered when conducting psychedelic research. Patients and their families are the most vulnerable to potential harm. Therefore, they should be treated with the same level of sensitivity that they would expect from an informed consent form.

Psychedelics can alter the structure of individual brain cells and help rewire neural pathways. This process is called neuroplasticity and can lead to an improved ability to process memories and feelings.

These drugs can even put the patient into a transient state that allows them to process their past trauma and experiences better, so they may emerge with a new perspective on these issues.

While research is still in its early stages, preliminary clinical trials have been encouraging. These results have the potential to be life-changing for those suffering from conditions such as addiction, post-traumatic stress disorder, and major depression. These findings have prompted more interest in psychedelic research, backed by an array of funding and academic centers.


Psychedelics are a fascinating class of drugs that cross the blood-brain barrier, which allows them to reach the brain’s serotonin receptors. Once inside the brain, they affect the body’s chemistry and can cause hallucinations and increased feelings of connectedness. These effects may make them useful in various areas, including addiction, psycho-oncology, and palliative care.

Despite their potential benefits, psychedelics have a complicated history and often have a terrible reputation in the public eye. This has influenced the way they are studied and used.

Researchers are now embarking on a new era of psychedelic research focused on facilitating neuroplasticity and improving mental health. This is achieved through the rewiring of connections within the brain. These changes may improve symptoms and alleviate suffering, allowing for a more productive life.

In addition, many clinical trials are testing the use of psychedelics in combination with intensive psychotherapy to treat various mental illnesses and disorders, including depression, anxiety, and trauma. This approach, gaining recognition, is believed to be effective in resetting the brain and breaking long-entrenched patterns of thought and behavior that contribute to severe psychiatric and physical illness.

However, there are still many questions about the safety of psychedelics and their effects on the brain and body. Several issues must be addressed to ensure a high-quality and transparent science, including the risk of abuse, addiction, overdose, and adverse reactions.

The best way to prevent these problems is by ensuring that researchers conduct their work under the strictest scientific rigor. This requires a rigorous review of the results, and it also means that researchers must be aware of their role in promoting safety.

To achieve these goals, a wide range of stakeholders must be involved in the dissemination process. This can include consumer groups, regulators, and funders. In addition, the dissemination process should involve the development of guidelines that are both practical and easy to understand.

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Where Does MDMA Come From?


MDMA, also known as 3,4-methylenedioxymethamphetamine, is a drug that has a long history of research and study. Currently, it is used for psychiatric purposes. It can be used in psychotherapy for anxiety and depression, and it has even been reported to be effective for treating PTSD.

The history of MDMA is an interesting one. There were various attempts to study it in the ’50s and ’60s. However, MDMA remained largely unstudied until the middle 1970s.

In the late 1970s, Rick Ingrasci became interested in psychedelic psychotherapy. He worked with ketamine to treat anxiety and he was convinced that MDMA had therapeutic potential.

In the early 1980s, a group of mental health practitioners argued against the DEA’s scheduling of MDMA. A court ordered the agency to reconsider its decision.

Chemical makeup

MDMA is a drug that has been used for many years in psychotherapy. In a clinical trial, MDMA was found to be effective in the treatment of PTSD. PTSD is a disorder characterized by a high level of anxiety and a fear of emotional injury.

MDMA is a chemical compound that is a weak 5-HT2B agonist. It acts on neurotransmitters that play a role in the regulation of eating behavior and responses to anxiogenic stimuli. The substance is also a reuptake inhibitor of membrane-bound transporters.

Although it has been used in therapy for a number of psychiatric disorders, including depression and bipolar disorder, its therapeutic effects are still uncertain. While it is considered safe, its use can be risky. Depending on how much is used, ecstasy can lead to serious health problems such as liver failure.


Ecstasy and MDMA are a class of drugs used by young people to experience a euphoric high. Although they may seem harmless at first, they have a number of health effects. They can lead to addiction, if they are used improperly.

The use of ecstasy and MDMA is dangerous. It can cause physical, mental, and emotional problems, including permanent damage to the body.

When a person uses ecstasy or MDMA, the brain releases a large amount of serotonin. This neurotransmitter is a neuromodulator that helps regulate sleep, digestion, pain management, and other bodily functions.

Serotonin is depleted after ecstasy use, which can lead to fatigue, lack of focus, and irregular sleeping patterns. A lack of serotonin can also contribute to depression and other emotional problems.

Medications for mental health conditions

Mental health medications can help manage a range of mental health conditions. Depression, bipolar disorder, and anxiety are all treatable with the right medication. These medications may be prescribed by a doctor or other healthcare professional.

When taking these medications, side effects are common. For instance, anti-psychotics can cause low blood pressure and dizziness. It is important to talk to your doctor about any side effects and how to avoid them. Some of these medications have to be tapered off slowly under doctor supervision.

Antidepressants are a class of drugs that prevent the re-uptake of neurotransmitters in the brain. They are often prescribed to treat depression. However, they have been used to treat other mental health conditions, including anxiety and ADHD.

Some of these medications are available off-label. Off-label is when a drug is prescribed for a purpose other than its initial approved use. This is a common practice for mental health conditions.

Common uses

MDMA is a psychoactive substance that acts as a central nervous system stimulant. It stimulates neurotransmitters, such as dopamine and serotonin. However, it also causes withdrawal symptoms. In addition, prolonged use of the drug can lead to tolerance and physical dependence.

The substance has been used as a party drug since the 1980s. It has been linked to increasing rates of death. There are many risks associated with using ecstasy, including liver damage and kidney failure. People may combine it with marijuana, alcohol, and other drugs.

The substance has been studied for its potential to treat depression, anxiety, and PTSD. However, clinical trials have yet to prove that the drug can work.

Its effects vary from person to person and depends on the dose. Some users experience nausea, confusion, muscle tension, and sleeplessness. Others seek to connect with other people and gain emotional insight.