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The Complete Guide on DMT

DMT, also known as N, or N-dimethyltryptamine, is a hallucinogenic drug. This hallucinogenic drug produces similar effects to other psychedelic drugs like LSD and psilocybin.

DMT is also refferred to as:

  • Spiritual molecule
  • Fantasia
  • Dimitri
  • Businessman’s special
  • Businessman’s trip
  • 45-minute psychosis

Despite the research being done on the possible medicinal benefits, DMT can have, it is still classified as a Schedule 1 controlled substance in the United States. This means that it is illegal to buy, possess, or distribute it. However, some cities have decriminalized DMT, but it’s still illegal under federal and state law.

DMT Facts

Some essential facts about DMT are:

  • DMT has been used for thousands of years.
  • Known as a “spirit molecule” drug
  • DMT has been used in Shamanic rituals in South America.

The History

DMT has been used in many religious ceremonies in South American countries and naturally occurs in many plants. Not only that but DMT can also be made in a lab.

Many users use this hallucinogenic drug for its psychoactive and hallucinogenic effects.

One of the most positive reported effects from users is a sense of “spiritual insight.”

Is DMT and Ayahuasca The Same?

Yes and no. DMT is the active ingredient in Ayahuasca. The difference between the two is that Ayahuasca is prepared using two plants called the Psychotria Viridis and Banisterioposis. At the same time, DMT contains MSOIs, that prevent the breakdown of DMT in the body.

Does DMT Natually Exist in The Brain?

As far as research goes, no one knows for sure. However, some experts believe that the pineal gland produces DMT in the brain and gets released when we dream.

Other experts believe that it’s released during birth and death. Some even go as far as claiming that the release of DMT at death may be the cause of near-death experiences many of us hear about.

What Does DMT Feel Like?

Experiences with DMT can vary; some may enjoy the trip while others may be overwhelmed or frightened.

A trip from DMT is described as “breaking out of a simulation” by many users. The effects are said to be more intense than other psychedelics. Users also report being able to access their inner minds and a feeling of being launched into other dimensions. Some describe traveling at high speeds through a tunnel of shapes and bright lights. Some may even feel like they have transformed into entirely different beings.

Language and time are not perceived or recognized during the trip. Users may experience telepathic communications with beings. DMT is regarded as having a completely different trip than LSD and magic mushrooms because users are taken into a whole other world instead of facing their problems or enhancing their mood.

How is DMT Consumed?

DMT usually comes in a white powder and can be either smoked, snorted, vaporized, or injected. 

In religious ceremonies, vines and plants are boiled to create tea.

How Long Does it Take to Feel The Effects of DMT?

The effects of DMT are rapid and occur within 5 to 10 minutes.

Plant-based tea brews, however, take as long as 20 to 60 minutes to take effect.

How Long Does DMT Last?

The duration and intensity of DMT depend on a few things:

  • How you took it: Inhaled, injected, or snorted last for 30 to 45 minutes.
  • The amount you use
  • Whether you took other drugs
  • Whether you have eaten

Drinking DMT in a brew like Ayahuasca will have long and lasting effects, up to 2 or 6 hours.

Harm Reduction Tips

Even though DMT exists naturally in many plant species, it is still a potent drug. So if you are going to try it for the first time, I suggest that you take a few precautionary steps to reduce any adverse reactions.

Don’t forget to keep these tips in mind when tripping on DMT:

  1. DO NOT trip on DMT alone. Do it with people you trust.
  2. Make sure to have at least one sober friend just in case anything goes wrong.
  3. Be sure to trip in a place you feel most comfortable in.
  4. It is better to sit or lie down during a DMT trip to avoid falling and injuring yourself.
  5. DO NOT combine DMT with other drugs so that you can avoid any adverse reactions.
  6. Pick a time when you feel positive to trip on DMT as the effects are pretty intense.
  7. DO NOT take DMT if you are taking antidepressants or have a heart condition or high blood pressure.
  8. And last but not least, DON’T FORGET to Test before using!

Conclusion

Like I’ve said before, DMT is a naturally occurring substance in many plant species and is extensively used in religious ceremonies in South America. Today, it’s used for its hallucinogenic effects.

If you plan on using DMT, do not forget to follow all the steps above to reduce your risk of any adverse reactions.

Moreover, as with all psychedelics, the “set” and “setting” are important factors determining whether the user will have a pleasant and positive experience or a bad trip. Set is the user’s mental state before tripping on DMT; these are your thoughts, expectations, and mood. The setting is the social and physical environment in which DMT is consumed. So being in a comfortable environment and with people, you trust will reduce the risk of a bad trip.

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How Psilocybin Can Change Your Life

Psilocybin changes everything. For those not familiar with psilocybin, it is the active ingredient in “magic mushrooms” that induces a hallucinogenic state and has a powerful and lasting impact on the human brain.

Recent research shows it could be helpful in the treatment of depression, PTSD, addiction, and other conditions and a tool to help terminal patients come to terms with death.

All well and significant, but how does this impact the average person who doesn’t struggle with any of the above conditions? That is what I have set out to discuss today. First, however, I want to talk about a few common misconceptions about psilocybin.

The History of Psilocybin

Despite its classification as a Schedule 1 narcotic, psilocybin is one of the safest psychoactive substances. Historians have traced its use back to some of the earliest known societies, and it has remained a key component of shamanistic rituals across the globe even to this day.

There is even pretty convincing evidence of cave paintings depicting the consumption of psilocybin mushrooms dating back tens of thousands of years.

The only non-theologian researcher on the initial team dedicated to studying the famous Dead Sea Scrolls concluded that early Christians ritualistically consumed psilocybin. He wrote a book about it called “The Sacred Mushroom and the Cross.”

Psilocybin is Far Safer Than Any Other Substance

You can argue that past societies may not have been aware of any potential harm elicited from the substance, but modern statistics lean in the mushroom’s favor as well. You can scour the internet and find maybe one or two fatalities EVER recorded, and those individuals had a pre-existing condition that made consumption of psilocybin dangerous.

Considering the estimate that millions of people use psilocybin each year in America alone, we are looking at a substance far safer than alcohol, tobacco, and the large majority of prescription medications. And no, it is not food poisoning. A small percentage of people who ingest psilocybin experience stomach discomfort, but the neurotoxicity rates for psilocybin are almost negligible.

An Eye-Opening Experience Like No Other

Of course, there is always the possibility of a “bad trip.” For those of you not familiar with this term, it is when the psychedelic experience becomes unpleasant or overly intense. It can happen when people take too large of a dose without proper mental preparation or enter with negative emotional baggage. A person’s setting or surroundings can even trigger it, so adequate preparation is so necessary.

However, all bad trips end, and although the experience may be unpleasant during its duration, many experienced psychedelic users have stated that bad trips can be seen as positive events as they often force people to confront their demons or negative thoughts.

Bad trips can happen, but most people who ingest psilocybin enjoy a pleasurable and reflective experience.

The Growth of New Brain Cells

Enough with the grim and gritty. Why should anyone even bother with psilocybin? The most profound benefit of psilocybin is neurogenesis. Neurogenesis is the growth of new brain cells.

In adults, this can only occur in a few select areas, the hippocampus being the most prominent and essential. What is critical is that neurogenesis in the hippocampus plays a significant role in learning and memory.

This is one reason why psilocybin is being researched to combat depression and PTSD. Suppose new neural pathways can be developed in patients struggling with particular traumatic memories or stagnant learning loops. In that case, we may fight the problem by bypassing the old connections in favor of new ones.

The best part about this type of therapy is that it could be achieved over just a few sessions instead of being on prescription drugs for the bulk of your remaining life. It could be a fix, as opposed to a Band-Aid.

What does this mean for you? Ever been in a tough mental rut? We all have. We suffer from the same external stimuli as everyone else.

Traumatic or unpleasant events can happen to us, and we often allow negative people or thoughts into our lives. This invariably affects us, decreases our focus, and can cause us to plateau or even regress.

Neurogenesis could be the solution. New neurons in the hippocampus mean new neural pathways and ultimately new ways of learning and analyzing past and future memories.

Why are depressed people encouraged to go out and try new things? For this exact reason. If you can develop a new pattern and a new mental pattern, you can bypass all kinds of negative thoughts, emotions, and habits.

This is why psilocybin has also shown to be wildly successful for those individuals trying to break stubborn habits like smokers trying to quit.

Benefits of Psilocybin

Neurogenesis alone is convincing evidence in favor of psilocybin use. However, it does not stop there. Low doses of psilocybin (doses too low to invoke hallucinations) increase visual acuity. Some theories maintain that early hominids took advantage of this to improve their hunting and survival skills.

In addition, psilocybin increases the stretch reflex of muscle tissue, unlike other substances like alcohol that harm your muscular system.

Other benefits of psilocybin:

  • Invokes natural curiosity and creativity,
  • Induces mystical experiences and
  • It has been known to diminish or destroy the ego temporarily.

All of these components help you experience the world in a brand new way, provide perspective and foster deep introspection. It is no surprise that many people who have tried psilocybin consider the experience the single most profound and spiritual experience of their lifetime.

Despite the benefits, many people are not able to distinguish the difference between illegal and immoral. Just because a substance is a Schedule 1 narcotic does not mean that its use is immoral and that those who partake in it are looked down upon. Instead, it is time to take a more critical eye to a select few of the substances on the Schedule 1 list and determine if the benefits of their use outweigh any potential physical or mental harm.

Psilocybin seems to be a clear-cut case to me, and fortunately, there is a growing movement in favor of its legalization. With marijuana blazing the way, the state of Washington has a large support base that is pushing for psilocybin to be the next state-legalized drug currently listed by the federal government as Schedule 1.

A New Era

Only time will tell if psilocybin will follow in the footsteps of marijuana. In the meantime, researchers at John Hopkins University and other renowned establishments will continue to study the substance and determine what long-term medical benefits exist.

So far, the results are promising. I know many of you will look at this information in a skeptical light as it probably runs counter to many of your ingrained belief systems. But I urge you to give this fungus a chance. Open up your mind to just the possibility that psilocybin might have a lasting and positive impact on select individuals and society as a whole.

Be cautious, be skeptical. But go and do your homework. Check out the excellent research that is being performed, and once educated, make your own decision.

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MDMA (Ecstasy) For Post-Traumatic Stress Disorder

Post-Traumatic Stress Disorder (PTSD) is surprisingly widespread, affecting eight million adults within the US yearly―of 10 % of all girls and 4 % of all males.

The popular present remedies for Post-Traumatic Stress Disorder (PTSD) are psychotherapy, mainly Cognitive Behavioral Therapy (CBT) and EMDR. As well as, consultants counsel that SSRI antidepressants could assist in some circumstances. However, these therapies don‘t work for an estimated 30 to 40 % of people living with PTSD.

For sufferers who don’t benefit from psychotherapy and SSRIs, MDMA has been proven to have as much as an 80-percent remedy relief.

Prevalence of PTSD

At one time, most of us dismissed PTSD as one thing that occurred solely in notable veterans, making it an uncommon situation. Although, the research presents that even among the many armies, PTSD is more widespread than we thought.

In line with research carried out by the Nationwide Institutes of Mental Health (NIMH), the Division of Veteran Affairs, and the Sidran Institute:

  • About eight percent of individuals within the US, or 24 million, have PTSD at any given time.
  • About 48 million adults have struggled with PTSD at some unspecified time in the future of their lives.
  • Amongst army veterans, over 17 % develop PTSD.
  • Those serving in Iraq and Afghanistan died from suicide ensuing from PTSD.
  • Amongst first responders, 32 % develop PTSD.

Who Develops PTSD?

The research presents that no less than 70 % of individuals have had extremely traumatic experiences. Nevertheless, most individuals recover from trauma. Solely 10 to 20 % of trauma exposures lead to PTSD.

Curiously, most circumstances of PTSD usually are not a result of combat or organized violence. Thirty-three percent of reported circumstances come from sexual violence reminiscent of rape or violence from a spouse. Moreover, 30 % developed PTSD from personal trauma from relationships, 12 % from interpersonal violence reminiscent of childhood bodily abuse or bodily assault, and 12 % from things like severe automotive accidents.

The prevalence of PTSD is more prominent within the US than in other countries. Girls are more prone to develop PTSD when faced with a traumatic experience than males. And trauma ensuing from intentional experiences is more likely to exacerbate PTSD than trauma ensuing from accidents or unintentional occasions.

Present Remedies For PTSD

The principal remedy for PTSD is a few forms of psychotherapy, and physicians could prescribe antidepressants for PTSD, notably SSRIs like Zoloft, Effexor, Prozac, or Paxil. The research presents that about 60% of sufferers get some aid from this medication, however solely 20 to 30% obtain complete remission of signs. Anti-anxiety medicines reminiscent of Benzodiazepines haven’t been confirmed valid.

Sure, psychotherapeutic methods have been confirmed helpful in PTSD remedies, most notably Cognitive Behavioral Therapy (CBT). This short-term form of therapy helps victims determine negative ideas and substitute them with positive ideas. A subtype of CBT, referred to as publicity therapy, directs victims to visualize traumatic experiences in therapeutic surroundings until the reminiscences do not respond. About 60 % of people with PTSD effectively recover from CBT.

One other helpful method is eye-movement desensitization and reprocessing (EMDR). The method has successful recovery rates (as much as 90 %) with single-trauma victims, though research differs in evaluating success in those affected by many traumas.

Prognosis For PTSD

It can be difficult to find an all-in-one cure for PTSD. Even with conventional psychotherapies, solely one-third of people living with PTSD recover within a year, and after ten years, one-third of people develop PTSD again. And whereas, as we’ve already talked about, psychotherapy and treatment have been confirmed considerably efficient with many sufferers (60 to 70 %), a significant group of trauma survivors doesn’t respond well to therapy due to remedy. That’s where MDMA comes into play.

What’s MDMA?

MDMA is a synthetic drug, the principal ingredient on the street known as“Ecstasy.” In line with the Nationwide Institutes of Mental Health (NIMH),

It produces an energizing impact, distortions in time and notion, and enhanced enjoyment from sensory experiences.

It has additionally been described as an entactogen—a drug that may enhance self-awareness and empathy.

MDMA impacts the mind in many methods. First, it considerably will increase the discharge of oxytocin, in any other case generally known as the “love hormone” and prolactin, which triggers leisure akin to a post-orgasmic state.

It additionally will increase the manufacturing of the neurotransmitter serotonin, which creates emotions of well-being. MDMA decreases exercise within the amygdala, which is the part of the mind related to concern, and the hippocampus, which controls reminiscence. With situation dampened and reminiscences fuzzy, sufferers can face previous traumas and face them.

Why MDMA?

As mentioned above, counseling and prescription drugs don’t work for all people living with PTSD. Due to its impact on the mind and nervous system, MDMA can ease a person’s traumas and process them.

In scientific research, MDMA has been confirmed efficient for 68 to 83% of sufferers who failed to recover from different therapies.

MDMA Therapeutic Protocol

If MDMA were legalized, it would solely be for psychotherapists skilled to provide sufferers with PTSD remedies. Sufferers couldn’t purchase the drug themselves. The scientific research thus far requires the sufferers to bear 12 weeks of structured psychotherapy. Throughout that point, they run several eight-hour days in which they take a dose of MDMA supervised by psychotherapists.

MDMA at the moment is taken into account as a Schedule 1 drug, which signifies that no one is authorized to prescribe it and is thought of as a harmful and dangerous drug. Nonetheless, dozen scientific trials have shown promising therapeutic results. Researchers hope that the outcomes will persuade legislators to legalize MDMA for medical use.

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MDMA-Assisted Therapy For PTSD: The Miracle Cure

The Iraq and Afghanistan wars brought the concept of PTSD to the forefront of America’s cultural consciousness. Seeing so many soldiers come back seemingly unable to process or cope with what they saw or did during their tours of duty shed light on our severe inability to help heal those suffering.

We also realized that it could affect far more than just combat veterans, and in the search to help heal those who have PTSD, many believe MDMA holds the key.

What Is PTSD?

While all of the hype around MDMA-assisted therapy for PTSD often centers around MDMA, it is critical to remember what this treatment aims to resolve.

PTSD (Post-Traumatic Stress Disorder) happens to those who have witnessed a traumatic event like a natural disaster, serious accident, combat, or those who have been personally assaulted.

They often relieve their experiences through nightmares or flashbacks and grow sad, angry, and detached from others. It can be difficult for patients to live everyday lives as seemingly benign events can “triggermemories of their traumatic experience, leading them to avoid everyday activities and places altogether.

We’re also learning PTSD doesn’t just affect someone with firsthand experience of an event. Those with secondary experience in an event such as police officers handling child abuse cases, emergency medical staff in a refugee camp, or even those working at inpatient drug rehab facilities can all experience PTSD.

It is estimated that 1 in 11 people will meet the criteria for a PTSD diagnosis in their lifetimes. That is a lot of people who need to heal.

Current PTSD Treatment Options

Pharmaceutical

Utilizing drugs like SSRIs (selective serotonin reuptake inhibitor) and SNRIs (selective norepinephrine reuptake inhibitor)

Therapy

Therapy such as Cognitive Processing Therapy, which focuses on patients’ reactions to traumatic events and helps them work through their “stuck points.”

EMDR

Short for eye movement desensitization and reprocessing, EMDR utilizes eye movement to help patients reprocess their trauma and negative self-perceptions.

However, we all know that antidepressants can be risky, and many patients are treatment-resistant to things like therapy and EMDR. This is where MDMA comes in.

MDMA Treatment Therapy For PTSD

What Is MDMA?

MDMA (3,4-Methylenedioxymethamphetamine) is an amphetamine.

In 1985 MDMA was classified as a Schedule 1 drug in the US, meaning it had no accepted medical value and a high potential for abuse.

MDMA, also called Ecstasy, is known for inducing euphoria, closeness, and empathy amongst users and is commonly used at dance raves and music festivals.

Unwanted Impurities That Cause Harm

To assess the therapeutic value of MDMA accurately, you must first test the drug for its pureness since it often contains amphetamines, PCP, cleaning supplies, and other harmful compounds.

Very rarely is Ecstasy pure MDMA, and thus Ecstasy containing unwanted impurities has adverse side effects.

Why Is Traditional Therapy Failing PTSD Patients?

Patients are often unable to process painful emotions because, understandably so, they cannot view the events from an objective perspective.

Their memory of the event is so inexorably tied with the feelings they felt during their experience that it is nearly impossible for patients to bypass these painful emotions to get to the actual event.

Many experts ascribe to the Emotional Processing Theory (EPT), which states that emotional processing begins only when patients can separate their emotions from the traumatic experience.

MDMA enables this separation more effectively than any other compound or therapy discovered thus far, which is why so many therapists believe it has the power to heal.

Why Does MDMA Improve Therapy?

MDMA increases the release of serotonin, prolactin, cortisol, and oxytocin in the brain.

An increase in oxytocin decreases our brain’s amygdala (the brain’s fear center) activation enabling patients to view their experience away from a place of fear.

Increased oxytocin also increases social bonding and improves patients’ ability to trust others, both of which PTSD patients struggle with.

MDMA Therapy For PTSD

MDMA is a tool used in therapy, but it is not the focal point. It is also important to remember that relatively few studies have been conducted using MDMA to treat PTSD, so there is no valid “standard” procedure yet.

With that said, the typical MDMA treatment consists of 15 total therapy sessions, only three of which involve MDMA.

The first three 90 minute therapy sessions do not include any MDMA and act to help therapists bond with patients.
Following the first three sessions, patients undergo their first MDMA session.

The MDMA Session

The actual MDMA session involves one male and one female therapist sitting with the patient, which has been shown to facilitate parental transference.

The therapists then engage in non-directive conversation with the patient, meaning they do not drive them toward any predetermined conclusions. Instead, therapists engage in the therapeutic alliance, anxiety management training, cognitive restructuring, and various other tactics to help patients effectively decouple their emotions from the traumatic incident.

What Is The Success Rate Of MDMA Therapy For PTSD?

While there are still relatively few studies done on MDMA-assisted PTSD treatment, they all show tremendous promise.

Patients had an improved mood, increased feelings of well-being, happiness, physical and mental relaxation, increased emotional sensitivity, and sociability.

Patients also feel more open and allow themselves to embrace intimacy in their relationships, something those struggling with PTSD have difficulty doing.

Combat veterans, in particular, cite MDMA as giving them an “ability to forgive themselves” for the atrocities they saw and were potentially part of throughout their time in combat.

The Numbers

CAPS (Clinical Administered PTSD Scale) is a system clinical physicians use to categorize a patient’s PTSD severity.

In one study, MDMA-assisted therapy reduced patients’ CAPS scores by 83%, compared to 25% in the control group that did not receive MDMA.

Several months after the study concluded, 14 of 16 patients stayed in remission (did not exhibit any PTSD symptoms) and reported long-lasting positive impacts from their participation in the study.

Of the three official Phase II trials of MDMA-assisted therapy to treat PTSD, 66% went into remission and saw their overall CAPS scores fall by 47%.

These numbers point to MDMA-assisted therapy as a far superior treatment option than traditional treatment options.

Is MDMA-Assisted Therapy For PTSD Safe?

As we mentioned before, it is imperative not to conflate MDMA with the street drug Ecstasy.

Administered in clinical settings, pure pharmaceutical MDMA is relatively safe.

No patients in the Phase II trials reported any long-term negative side-effects from their participation in the studies.

When Will MDMA-Assisted Therapy Be Legal?

The driving organization behind the legalization of MDMA for therapeutic use has been the Multidisciplinary Association For Psychedelic Studies (MAPS).

Thanks to MAPS, the FDA officially approved the first Phase III trial involving MDMA-assisted therapy.

MDMA has also recently achieved “breakthrough” status from the FDA, fast-tracking it to legalization in clinical settings.

If there are no further significant obstacles, MAPS foresees 2021 as the year MDMA-assisted therapy for PTSD is finally a mainstream clinical practice.

MDMA-assisted PTSD treatment has the potential to help millions cope with and heal from their traumatic experiences.

We look forward to the day when patients can safely, effectively, and legally pursue this avenue of treatment.