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MDMA (Ecstasy) For Post-Traumatic Stress Disorder

MDMA (Ecstasy) For Post-Traumatic Stress Disorder

Post-Traumatic Stress Disorder (PTSD) is surprisingly widespread, affecting eight million adults within the US yearly―of 10 % of all girls and 4 % of all males.

The popular present remedies for Post-Traumatic Stress Disorder (PTSD) are psychotherapy, mainly Cognitive Behavioral Therapy (CBT) and EMDR. As well as, consultants counsel that SSRI antidepressants could assist in some circumstances. However, these therapies don‘t work for an estimated 30 to 40 % of people living with PTSD.

For sufferers who don’t benefit from psychotherapy and SSRIs, MDMA has been proven to have as much as an 80-percent remedy relief.

Prevalence of PTSD

At one time, most of us dismissed PTSD as one thing that occurred solely in notable veterans, making it an uncommon situation. Although, the research presents that even among the many armies, PTSD is more widespread than we thought.

In line with research carried out by the Nationwide Institutes of Mental Health (NIMH), the Division of Veteran Affairs, and the Sidran Institute:

  • About eight percent of individuals within the US, or 24 million, have PTSD at any given time.
  • About 48 million adults have struggled with PTSD at some unspecified time in the future of their lives.
  • Amongst army veterans, over 17 % develop PTSD.
  • Those serving in Iraq and Afghanistan died from suicide ensuing from PTSD.
  • Amongst first responders, 32 % develop PTSD.

Who Develops PTSD?

The research presents that no less than 70 % of individuals have had extremely traumatic experiences. Nevertheless, most individuals recover from trauma. Solely 10 to 20 % of trauma exposures lead to PTSD.

Curiously, most circumstances of PTSD usually are not a result of combat or organized violence. Thirty-three percent of reported circumstances come from sexual violence reminiscent of rape or violence from a spouse. Moreover, 30 % developed PTSD from personal trauma from relationships, 12 % from interpersonal violence reminiscent of childhood bodily abuse or bodily assault, and 12 % from things like severe automotive accidents.

The prevalence of PTSD is more prominent within the US than in other countries. Girls are more prone to develop PTSD when faced with a traumatic experience than males. And trauma ensuing from intentional experiences is more likely to exacerbate PTSD than trauma ensuing from accidents or unintentional occasions.

Present Remedies For PTSD

The principal remedy for PTSD is a few forms of psychotherapy, and physicians could prescribe antidepressants for PTSD, notably SSRIs like Zoloft, Effexor, Prozac, or Paxil. The research presents that about 60% of sufferers get some aid from this medication, however solely 20 to 30% obtain complete remission of signs. Anti-anxiety medicines reminiscent of Benzodiazepines haven’t been confirmed valid.

Sure, psychotherapeutic methods have been confirmed helpful in PTSD remedies, most notably Cognitive Behavioral Therapy (CBT). This short-term form of therapy helps victims determine negative ideas and substitute them with positive ideas. A subtype of CBT, referred to as publicity therapy, directs victims to visualize traumatic experiences in therapeutic surroundings until the reminiscences do not respond. About 60 % of people with PTSD effectively recover from CBT.

One other helpful method is eye-movement desensitization and reprocessing (EMDR). The method has successful recovery rates (as much as 90 %) with single-trauma victims, though research differs in evaluating success in those affected by many traumas.

Prognosis For PTSD

It can be difficult to find an all-in-one cure for PTSD. Even with conventional psychotherapies, solely one-third of people living with PTSD recover within a year, and after ten years, one-third of people develop PTSD again. And whereas, as we’ve already talked about, psychotherapy and treatment have been confirmed considerably efficient with many sufferers (60 to 70 %), a significant group of trauma survivors doesn’t respond well to therapy due to remedy. That’s where MDMA comes into play.

What’s MDMA?

MDMA is a synthetic drug, the principal ingredient on the street known as“Ecstasy.” In line with the Nationwide Institutes of Mental Health (NIMH),

It produces an energizing impact, distortions in time and notion, and enhanced enjoyment from sensory experiences.

It has additionally been described as an entactogen—a drug that may enhance self-awareness and empathy.

MDMA impacts the mind in many methods. First, it considerably will increase the discharge of oxytocin, in any other case generally known as the “love hormone” and prolactin, which triggers leisure akin to a post-orgasmic state.

It additionally will increase the manufacturing of the neurotransmitter serotonin, which creates emotions of well-being. MDMA decreases exercise within the amygdala, which is the part of the mind related to concern, and the hippocampus, which controls reminiscence. With situation dampened and reminiscences fuzzy, sufferers can face previous traumas and face them.


As mentioned above, counseling and prescription drugs don’t work for all people living with PTSD. Due to its impact on the mind and nervous system, MDMA can ease a person’s traumas and process them.

In scientific research, MDMA has been confirmed efficient for 68 to 83% of sufferers who failed to recover from different therapies.

MDMA Therapeutic Protocol

If MDMA were legalized, it would solely be for psychotherapists skilled to provide sufferers with PTSD remedies. Sufferers couldn’t purchase the drug themselves. The scientific research thus far requires the sufferers to bear 12 weeks of structured psychotherapy. Throughout that point, they run several eight-hour days in which they take a dose of MDMA supervised by psychotherapists.

MDMA at the moment is taken into account as a Schedule 1 drug, which signifies that no one is authorized to prescribe it and is thought of as a harmful and dangerous drug. Nonetheless, dozen scientific trials have shown promising therapeutic results. Researchers hope that the outcomes will persuade legislators to legalize MDMA for medical use.

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